Association of CCL2, CCR5, ELMO1, and IL8 Polymorphism with Diabetic Nephropathy in Malaysian Type 2 Diabetic Patients

Table 5

Differences in the frequencies of allele distribution among the races.

SNP	Control							Case
	Malay		Chinese		Indian		P value	Case		Control		Indian		P value
							χ2							χ2
							df=2
														df=2
CCR5	G=128	A=64	G=102	A=55	G=166	A=106	0.432	G=163	A=99	G=108	A=108	G=102	A=70	0.023
rs1799987	(66.7)	(33.3)	(71.1)	(28.9)	(61)	(39.0)	1.68	(62.2)	(37.8)	(50)	(50)	(59.3)	(40.7)	7.57
CCL2	I=111	D=81	I=104	D=86	I=144	D=96	1.200	I=99	D=121	I=109	D=107	I=62	D=62	<0.001
rs3917887	(57.8)	(42.2)	(54.7)	(45.3)	(60.0)	(40.0)	0.549	(45.0)	(55.0)	(50.5)	(49.5)	(36.9)	(63.1)	28.24
IL8	T=122	A=70	T=120	A=70	T=176	A=96	0.9371	T=156	A=106	T=156	A=73	T=97	A=75	0.004
rs4073	(63.5)	(36.5)	(63.2)	(36.8)	(64.7)	(35.3)	0.13	(59.4)	(40.6)	(68.0)	(32.0)	(56.4)	(43.6)	6.56
ELMO1	A=114	G=78	A=128	G=62	A=173	G=99	0.2671	A=158	G=104	A=131	G=85	A=111	G=61	0.641
rs741301	(59.4)	(40.6)	(67.4)	(32.6)	(63.6)	(36.4)	2.34	(60.3)	(36.7)	(60.6)	(39.4)	(64.5)	(35.5)	0.89

<0.05 indicates the significant difference of allele distribution in the population.