An Efficient Chemoenzymatic Process for Preparation of Ribavirin

Table 2

The Ribavirin synthesis with different biocatalytical systems.

Donor	Biocatalyst	Conversion, %	Reference
Uridine	A. hydrophila CECT4226	65	[9]
Guanosine	GA-E. coli BMT 4D/1A	70	[10]
Uridine	pET-30a-udp-deoD	84	[14]
Uridine	ATCC 12407	86	[16]
Guanosine	BL21(DE3)/pERPUPHHO1	97	This study