Thermal Hazards of Synthesizing a Grignard Reagent under Different Dosing Rates

Table 4

Risk matrix for synthesis of Grignard reagent at different dosing rates.

Dosing rate/K⋅min^−1	ΔTad,d/K	Severity	TMRad/h	Possibility	Risk level
2	204.87	Serious factory losses	>24	Infrequent	I: acceptable
1	191.53	Short-term damage of factories	>24	Infrequent	I: acceptable
0.5	177.34	Short-term damage of factories	>24	Infrequent	I: acceptable