Research Article

Antithrombotic Therapy Improves ICU Mortality of Septic Patients with Peripheral Vascular Disease

Table 1

Characteristics among groups before IPW. AP, antiplatelet group; AC, anticoagulant group; AC-AP, antiplatelet-anticoagulation group; and non-AT, the group that did not receive antithrombotic treatment.

CharacteristicsNon-AT groupAP groupAC groupAC-AP groupP value

Age (median, IQR)75.5 (66.8, 83.3)73.6 (66.5, 80.7)74.3 (62.5, 83)73.7 (65.4, 81.2)0.196
Gender (n, %)0.608
Female89 (43.4)57 (42.5)80 (49.1)128 (46.7)
Male116 (56.6)77 (57.5)83 (50.9)146 (53.3)
CRRT (n, %)0.324
No198 (96.6)130 (97)152 (93.3)259 (94.5)
Yes7 (3.4)4 (3)11 (6.7)15 (5.5)
Alcoholism (n, %)0.054
No199 (97.1)128 (95.5)150 (92)266 (97.1)
Yes6 (2.9)6 (4.5)13 (8)8 (2.9)
Heart failure (n, %)0.537
No94 (45.9)65 (48.5)76 (46.6)114 (41.6)
Yes111 (54.1)69 (51.5)87 (53.4)160 (58.4)
Hypertension0.024
No67 (32.7)27 (20.1)47 (28.8)62 (22.6)
Yes138 (67.3)107 (79.9)116 (71.2)212 (77.4)
Diabetes (n, %)0.319
No104 (50.7)68 (50.7)93 (57.1)131 (47.8)
Yes101 (49.3)66 (49.3)70 (42.9)143 (52.2)
Obesity (n, %)0.175
No193 (94.1)123 (91.8)156 (95.7)248 (90.5)
Yes12 (5.9)11 (8.2)7 (4.3)26 (9.5)
Renal failure (n, %)0.274
No114 (55.6)88 (65.7)97 (59.5)156 (56.9)
Yes91 (44.4)46 (34.3)66 (40.5)118 (43.1)
Liver disease (n, %)0.573
No190 (92.7)123 (91.8)145 (89)253 (92.3)
Yes15 (7.3)11 (8.2)18 (11)21 (7.7)
Sofa (median, IQR)4 (3, 6)6 (4, 7)5 (3.5, 7)5 (3, 7.8)0.013
INR (median, IQR)1.2 (1.1, 1.5)1.2 (1.1, 1.6)1.3 (1.1, 1.8)1.2 (1.1, 1.6)0.668
PT (median, IQR)13.9 (12.9, 16.1)14.3 (12.9, 16.7)14.5 (12.9, 19.1)13.9 (12.8, 16.8)0.398
PPT (median, IQR)30.1 (26.5, 36)32 (26.4, 39.1)30.8 (26.9, 36.9)30.4 (26.4, 38)0.561
SpO2 (median, IQR)97.2 (96, 98.5)97.9 (96.5, 98.8)97.7 (96.4, 98.7)97.6 (96.2, 98.7)0.086