Review Article
Hematopoietic Stem Cell Transplantation for Acute Myeloid Leukemia: An Overview of Systematic Reviews
Table 4
Main meaningful outcome comparison in included reviews.
| Author (y) | Type of patients | Intervention | Outcome(s) | OS | DFS | RFS | TRM | RR | Survival from relapse | Death rate | Relapse or death rate |
| Li (2019) [27] | Patients with intermediate-risk AML in CR1 | Allo-SCT | HR = 0.84(0.73–0.97) | | HR = 0.82(0.73–0.92) | HR = 4.16(3.37–5.15) | HR = 0.53(0.42–0.66) | | | | Li (2015) [26] | Patients with intermediate-risk AML in CR1 | Allo-SCT | HR = 0.43(0.22–0.84) | | HR = 0.68(0.48–0.95) | HR = 3.09(1.38–6.92) | HR = 0.58(0.45–0.75) | | | | Ma (2015) [25] | FLT3/ITD AML patients | Allo-SCT | OR = 2.88(2.04–4.05) | OR = 2.84(1.89–4.25) | | | OR = 0.09(0.05–0.18) | | | | Koreth (2009) [31] | AML patients in CR1 | Allo-SCT | HR = 0.90(0.82–0.97) | | HR = 0.80(0.74–0.86) | | | | | | Jing (2010) [29] | AML patients in CR1 | Allo-SCT | HR = 1.05(0.91–1.21) | HR = 0.89(0.80–0.98) | | RR = 1.90(1.34–2.70) | RR = 0.79(0.72–0.87) | HR = 2.09(1.41–3.08) | | | Koreth (2009) [31] | AML patients in CR1 | Allo-SCT | HR = 0.90(0.82–0.97) | | HR = 0.80(0.74–0.86) | | | | | | Levi (2004) [34] | AML patients in CR1 | ABMT | | | | | | | RR = 0.94(0.84–1.09) | RR = 0.85(0.75–0.97) | Nathan (2004) [33] | Adult patients with AML | ABMT | 1.01(0.89–1.15) | 1.24(1.06–1.44) | | OR = 2.63(1.60–4.32) | | | | | Levi (2004) [34] | AML patients in CR1 | ABMT | | | | | | RR = 0.94(0.84–1.09) | RR = 0.85(0.75–0.97) | |
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