Research Article
Free Triiodothyronine Is Associated with Poor Outcomes after Acute Ischemic Stroke
Table 1
Baseline characteristics (demographic, clinical, and laboratory data) according to the functional status at 3 months.
| | Variable | Good outcome (n = 236) | Poor outcome (n = 244) | value |
| | Age (years) | 64.53 ± 14.22 | 70.11 ± 12.02 | <0.001 | | Women (n, %) | 69 (29.2) | 107 (43.8) | 0.001 | | BMI (kg/m2) | 23.5 ± 3.2 | 23.1 ± 3.2 | 0.213 | | Smoking (n, %) | 78 (33.0) | 76 (31.1) | 0.655 | | Alcohol consumption (n, %) | 64 (27.1) | 57 (23.3) | 0.343 | | History of stroke (n, %) | 23 (9.7) | 26 (10.6) | 0.742 | | Hypertension (n, %) | 131 (55.5) | 144 (59.0) | 0.437 | | AF (n, %) | 50 (21.1) | 101 (41.4) | <0.001 | | DM (n, %) | 60 (25.4) | 64 (26.2 | 0.840 | | CHD/HF (n, %) | 47 (19.9) | 81 (33.2) | 0.001 | | SBP at admission | 140.58 ± 25.82 | 142.27 ± 22.76 | 0.449 | | DBP at admission | 81.86 ± 15.78 | 80.40 ± 14.53 | 0.293 | | Hemoglobin (g/L) | 139.09 ± 17.87 | 134.14 ± 20.15 | 0.005 | | Platelet (10^9/L) | 181.20 ± 60.95 | 173.41 ± 66.84 | 0.183 | | White blood cell (10^9/L) | 7.63 ± 2.75 | 8.48 ± 3.16 | 0.002 | | Glu (mmol/L) | 7.97 ± 3.31 | 8.27 ± 3.30 | 0.316 | | Albumin (g/L) | 42.41 ± 4.15 | 40.70 ± 4.09 | <0.001 | | eGFR (ml/min/1.73 m2) | 85.12 ± 19.29 | 79.69 ± 21.62 | 0.004 | | Uric acid (μmol/L) | 363.86 ± 106.12 | 349.23 ± 106.93 | 0.162 | | TG (mmol/L) | 1.35 (0.93–2.05) | 1.23 (0.88–1.73) | 0.05 | | TC (mmol/L) | 4.40 ± 1.04 | 4.26 ± 0.91 | 0.055 | | HDL (mmol/L) | 1.24 ± 0.35 | 1.27 ± 0.37 | 0.334 | | NIHSS score | 3 (2–7) | 13 (8–17) | <0.001 | | TOAST classification | | LAA (n, %) | 65 (27.5) | 94 (38.5) | <0.001 | | CE (n, %) | 51 (21.6) | 94 (38.5) | | SAO (n, %) | 93 (39.4) | 36 (14.8) | | Unclassified (n, %) | 27 (11.4) | 20 (8.2) | | Recanalized therapy (n, %) | 60 (25.4) | 91 (37.2) | 0.005 | | TSH (mU/L) | 1.97 (1.29–3.22) | 1.29 (0.73–2.51) | <0.001 | | FT3 (pmol/L) | 4.04 ± 0.68 | 3.53 ± 0.70 | <0.001 | | FT4 (pmol/L) | 16.05 ± 2.55 | 16.64 ± 2.69 | 0.014 |
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BMI: body mass index; AF: atrial fibrillation; DM: diabetes mellitus; CHD: coronary heart disease; HF: heart failure; eGFR: estimated glomerular filtration rate; TG: triglyceride; TC: total cholesterol; HDL-C: high-density lipoprotein cholesterol; Glu: glucose; NIHSS: National Institutes of Health Stroke Scale; TOAST: Trial of Org 10172 in Acute Stroke Treatment; LAA: large-artery atherosclerosis; CE: cardioembolism; SAO: small-artery occlusion; TSH: thyroid-stimulating hormone; FT3: free triiodothyronine; FT4: free thyroxine.
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