Research Article

Early Diagnosis of Abnormal Left Ventricular Systolic Functions of Rare Pathogenic Titin Mutation Gene Carriers in FHCM by Three-Dimensional Speckle Tracking Echocardiography Combined with Gene Detection

Table 2

Comparison of two-dimensional echocardiography between the two groups ( ± s).

IndexNoncarrier group (n = 12)Carrier group (n = 4)

IVSD (mm)7.50 ± 0.708.95±1.210.011
LVPWD (mm)7.40 ± 0.518.91±0.930.042
LVEDV (ml)83.28 ± 15.9681.52 ± 10.280.101
LVESV (ml)28.36 ± 8.5128.40 ± 6.250.280
LVEF (%)65.64 ± 6.3265.49 ± 5.250.196
SV (ml)53.22 ± 9.8652.77 ± 4.100.521
IVRT (ms)76.51 ± 9.4578.00 ± 20.140.793
LVMI (g/cm2)46.04 ± 2.9152.03±5.220.017
LAVI (ml/cm2)18.10 ± 3.8419.01 ± 9.840.602
Ea9.41 ± 1.266.87±0.760.002
Ea/Aa1.22 ± 0.340.81±0.190.036
E70.61 ± 3.2756.42±6.210.000
E/Ea7.38 ± 0.528.17±0.810.007

Compared with the noncarrier group,  < 0.05. The bold values are indexes,  < 0.05.