Early Diagnosis of Abnormal Left Ventricular Systolic Functions of Rare Pathogenic Titin Mutation Gene Carriers in FHCM by Three-Dimensional Speckle Tracking Echocardiography Combined with Gene Detection

Table 5

ROC curve analysis results of GLS and conventional 2DE-related indicators.

Index	Cut-off value	Area under the curve	95%CI		Sensitivity (%)	Specificity (%)
IVSD	8.22	0.85	0.64–0.99	0.021	75	83
LVPWD	8.15	0.83	0.69–0.99	0.011	69	92
LVMI	50.50	0.89	0.64–0.99	0.021	75	90
GLS	−21.24	0.89	0.64–0.99	0.021	75	92

IVSD: interventricular septum diastolic dimension, LVPWD: left ventricular end-diastolic posterior wall dimension, LVMI: left ventricular mass index, and GLS: global longitudinal strain.