Research Article

Investigating the Relationship between Knowledge and Hepatotoxic Effects with Medication Adherence of TB Patients in Banyumas Regency, Indonesia

Table 1

Relationship between knowledge level and hepatotoxic effect with patient adherence.

AdherenceTotal (91) Value
Low (%)High (%)

Knowledge level
 High (>75%)2 (12.5%)14 (87.5%)16<0.001
 Moderate (60-74%)6 (18.8%)26 (81.2%)32
 Poor (<60%)36 (83.7%)7 (16.3%)43

Hepatotoxic Effect
Grade 1 (Mild) (AST/ALT 51–125 U/L)13 (23.3%)43 (76.8%)56<0.001
Grade 2 (Moderate) (AST/ALT 126–250 U/L)30 (88.2%)4 (11.8%)34
Grade 3 (Severe) (AST/ALT 251–500 U/L)1 (100%)0 (0%)1