Research Article

Peripheral Tumor Location Predicts a Favorable Prognosis in Patients with Resected Small Cell Lung Cancer

Table 2

Patient distribution and characteristics associated with DFS and OS.

VariableDFSOS
Number (%)Medium (months), HR (95% CI) valueNumber (%)Medium (months), HR (95% CI) value

Gender0.30770.0915
 Male76 (63.9)31.6, 1.318 (0.790–2.197)71 (63.4)57.3, 1.666 (0.957–2.899)
 Female43 (36.1)70.2, 0.759 (0.455–1.266)41 (36.6)NR, 0.600 (0.345–1.045)
Age (years)0.67290.9895
 <6595 (79.8)35.9, 1.110 (0.688–1.791)89 (79.5)NR, 1.004 (0.517–1.953)
 ≥6524 (20.2)73.3, 0.901 (0.558–1.453)23 (20.5)58.6, 0.996 (0.512–1.935)
Smoking status0.26780.0616
 Never-smokers43 (36.1)NR, 0.741 (0.445–1.234)39 (34.8)NR, 0.583 (0.334–1.019)
 Current smokers76 (63.9)28.0, 1.349 (0.810–2.247)73 (65.2)63, 1.715 (0.982–2.997)
TNM stage<0.0001<0.0001
 I55 (46.2)NR, 0.444 (0.215–0.918)54 (48.2)NR, 0.528 (0.239–1.167)
 II28 (23.5)23.6, 0.649 (0.360–1.172)26 (23.2)37.9, 0.500 (0.260–0.963)
 III36 (30.3)11.8, 3.388 (1.798–6.384)32 (28.6)20.7, 3.643 (1.815–7.313)
T stage0.11880.0581
 T176 (63.9)NR, 0.672 (0.395–1.142)72 (64.3)NR, 0.568 (0.317–1.020)
 T243 (36.1)23.6, 1.489 (0.876–2.531)40 (35.7)32.2, 1.759 (0.981–3.157)
N stage0.00040.0001
 N060 (50.4)NR, 0.571 (0.269–1.212)59 (52.7)NR, 0.808 (0.355–1.837)
 N123 (19.3)34.3, 0.551 (0.296–1.026)21 (18.7)NR, 0.395 (0.198–0.790)
 N236 (30.3)12.1, 2.871 (1.558–5.292)32 (28.6)20.7, 3.083 (1.575–6.037)

NR, not reached.