Peripheral Tumor Location Predicts a Favorable Prognosis in Patients with Resected Small Cell Lung Cancer

Table 3

Multivariate analysis for DFS and OS in resected LS SCLC.

Variable	DFS			OS
	HR	95% CI	value	HR	95% CI	value
Gender (female vs. male)	0.793	0.450–1.398	0.422	0.615	0.323–1.172	0.140
Age (≥ 65 y vs. <65 y)	1.179	0.601–2.314	0.632	1.175	0.580–2.381	0.655
Smoking status (current vs. never)	1.138	0.627–2.066	0.672	1.330	0.689–2.568	0.396
TNM stage (III vs. II vs. I)	4.310	1.317–14.101	0.016	3.892	1.160–13.062	0.028
T stage (T2 vs. T1)	0.981	0.561–1.717	0.947	1.050	0.572–1.930	0.874
N stage (N2 vs. N1 vs. N0)	0.419	0.137–1.274	0.125	0.490	0.159–1.510	0.214
Tumor location (peripheral vs. central)	0.471	0.276–0.804	0.006	0.495	0.276–0.888	0.018
Adjuvant chemo (yes vs. no)	1.216	0.670–2.206	0.520	1.133	0.604–2.125	0.697
Adjuvant radio (yes vs. no)	1.140	0.413–3.146	0.800	1.035	0.334–3.204	0.953
PCI (yes vs. no)	0.746	0.220–2.533	0.639	0.385	0.050–2.940	0.357