The Relationship of Partial Pressure of Carbon Dioxide (PaCO₂) with Disease Severity Indicators Such as BODE and GOLD in Hospitalized COPD Patients

Table 2

Demographic and laboratory characteristics of COPD patients according to PaCO₂ median.

	PaCO2 < 42.7 (n = 39)	PaCO2 ≥ 42.7 (n = 41)
Age (years)	72.87 ± 8.10	70.24 ± 7.17	0.128
Sex (male, n%)	32 (82.05%)	33 (80.49%)	0.858
Duration of disease (years)	8 (3–12)	11.5 (5.75–21)	0.116
Smoking (n%)	29 (74.36%)	32 (78.05%)	0.854
BMI (kg/m^2)	21.52 ± 3.76	20.48 ± 3.62	0.218
pH	7.42 ± 0.03	7.39 ± 0.04	<0.001
pH on day 7 of admission	7.41 ± 0.04	7.39 ± 0.03	0.035
WBC (×10 ^∗ 9/L)	8.15 ± 4.04	7.18 ± 2.67	0.209
Albumin (g/L)	34.74 ± 3.66	36.29 ± 2.96	0.049
FEV1 (L)	1.12 ± 0.40	0.79 ± 0.29	<0.001
FVC (L)	2.05 ± 0.62	1.63 ± 0.43	0.001
FEV1/FVC	54.66 ± 9.41	47.95 ± 9.01	0.003
FEV1%	46.96 ± 12.78	34.09 ± 13.85	<0.001
GOLD	2.69 ± 0.68	3.23 ± 0.77	0.002
BODE	3.34 ± 2.07	4.58 ± 2.63	0.030
mMRC	2 (1-2)	1 (1-2)	0.211
SGRQ	34.27 ± 15.42	43.30 ± 20.01	0.030
PaO2 (mmHg)	75.80 ± 9.70	70.80 ± 16.49	0.101

Data are presented as mean ± SD unless indicated otherwise. COPD, chronic obstructive pulmonary disease; BMI, body mass index; WBCs, white blood cells; FEV₁, forced expiratory volume in 1 second; FVC, forced vital capacity; FEV₁%, FEV₁ in percent of the predicted value; GOLD, Global Initiative for Chronic Obstructive Lung Disease; BODE, BMI, airway obstruction, dyspnea, and exercise capacity; mMRC, modified Medical Research Council dyspnea score; SGRQ, St. George’s Respiratory Questionnaire; PaO₂, partial pressure of oxygen in arterial blood; PaCO₂, partial pressure of carbon dioxide in arterial blood; SD, standard deviation.