Research Article

The Relationship of Partial Pressure of Carbon Dioxide (PaCO2) with Disease Severity Indicators Such as BODE and GOLD in Hospitalized COPD Patients

Table 3

Correlations between lung function, severity of disease, other indicators, and PaCO2.

VariablesPaCO2
r

Age (years)−0.2540.023
Duration of disease (years)0.1650.145
BMI (kg/m2)−0.2390.034
pH−0.639<0.001
pH on day 7 of admission−0.586<0.001
WBC (×10  9/L)−0.0010.996
Albumin (g/L)0.1090.358
FEV1 (L)−0.523<0.001
FVC (L)−0.486<0.001
FEV1/FVC−0.3770.001
FEV1%−0.612<0.001
GOLD0.558<0.001
BODE0.505<0.001
mMRC0.1770.122
SGRQ0.2990.008
PaO2 (mmHg)0.1690.133

COPD, chronic obstructive pulmonary disease; BMI, body mass index; WBCs, white blood cells; FEV1, forced expiratory volume in 1 second; FVC, forced vital capacity; FEV1%, FEV1 in percent of the predicted value; GOLD, Global Initiative for Chronic Obstructive Lung Disease; BODE, BMI, airway obstruction, dyspnea, and exercise capacity; mMRC, modified Medical Research Council dyspnea score; SGRQ, St. George’s Respiratory Questionnaire; PaO2, partial pressure of oxygen in arterial blood; PaCO2, partial pressure of carbon dioxide in arterial blood.