The Relationship of Partial Pressure of Carbon Dioxide (PaCO₂) with Disease Severity Indicators Such as BODE and GOLD in Hospitalized COPD Patients

Table 4

Univariate logistic regression analyses of factors for BODE ≥ 5.

	OR	95% CI
Age (years)	0.983	0.922–1.049	0.605
Sex (male)	0.959	0.262–3.510	0.950
Duration of disease (years)	1.050	0.973–1.133	0.213
Smoking	0.900	0.269–3.015	0.864
BMI	0.734	0.607–0.887	0.001
pH^∗	0.745	0.619–0.897	0.002
WBC	0.859	0.703–1.051	0.140
Albumin	0.886	0.735–1.068	0.205
FEV1/FVC	0.884	0.821–0.952	0.001
FEV1%	0.902	0.854–0.953	<0.001
GOLD
<3	1.000
≥3	0.145	0.031–0.693	0.015
mMRC
<2	1.000
≥2	0.034	0.008–0.145	<0.001
SGRQ
<25	1.000
≥25	0.222	0.046–1.070	0.061
PaCO2	1.146	1.047–1.253	0.003
PaO2	0.990	0.952–1.029	0.596

COPD, chronic obstructive pulmonary disease; BMI, body mass index; WBCs, white blood cells; FEV₁, forced expiratory volume in 1 second; FVC, forced vital capacity; FEV₁%, FEV₁ in percent of the predicted value; GOLD, Global Initiative for Chronic Obstructive Lung Disease; BODE, BMI, airway obstruction, dyspnea, and exercise capacity; mMRC, modified Medical Research Council dyspnea score; SGRQ, St. George’s Respiratory Questionnaire; PaO₂, partial pressure of oxygen in arterial blood; PaCO₂, partial pressure of carbon dioxide in arterial blood; pH∗, the data were present according to pH∗100.