Elevated Cardiac Troponin I following Asymptomatic Intradialytic Hypotension: A Pilot Study with a 2-Year Follow-Up

Table 1

Baseline characteristics of the study group.

	All patients (N = 70)	Non-IDH patients (N = 43)	IDH patients (N = 27)		value
			Negative cTnI (N = 21)	Positive cTnI (N = 6)
Age (years), mean ± SD	58.4 ± 12	57.6 ± 13	61.6 ± 10	53.3 ± 13	0.273
Male, N (%)	34 (48)	18 (42)	12 (57)	4 (67)	0.336
Female, N (%)	36 (52)	25 (58)	9 (43)	2 (33)	0.336
Dialytic age (months), mean ± SD	35.6 ± 33	34.9 ± 35	38.3 ± 30	30.8 ± 33	0.872
BMI (kg/m^2), mean ± SD	25.7 ± 5	25.2 ± 5	26.8 ± 4	26.1 ± 5	0.493
BF (mL/min), median (IQR)	252.2 (26)	246.5 (27)	257.1 (14)	276.6 (38)	0.018
UF (mL/h), mean ± SD	566.1 ± 134.1	546.5 ± 136.4	571.4 ± 101.3	687.5 ± 172.3	0.051
BUN (mg/dL), mean ± SD	53.0 ± 19	54.3 ± 20	54.3 ± 19	38.6 ± 8	0.174
Cr (mg/dL), mean ± SD	6.6 ± 2	6.4 ± 2	6.8 ± 3	7.1 ± 2	0.678
Albumin (mg/dL), mean ± SD	3.5 ± 1	3.44 ± 0.5	3.7 ± 2	3.8 ± 0.7	0.510
ESR (mm/h), mean ± SD	33.2 ± 27	36.5 ± 31	27.4 ± 20	29.6 ± 16	0.441
CRP (mg/L), mean ± SD	16.3 ± 20	19.8 ± 23	11.7 ± 13	8.0 ± 6	0.189
Ferritin (mcg/L), mean ± SD	454.8 ± 322	500.7 ± 369	366.7 ± 209	434.1 ± 250	0.295
PTH (pg/mL), mean ± SD	322.9 ± 314	320.8 ± 322	311.6 ± 293	377.3 ± 370	0.903
Vitamin D (pg/mL), mean ± SD	26.8 ± 16	25.5 ± 16	27.6 ± 17	33.3 ± 15	0.546
MPV (fL), mean ± SD	8.8 ± 1	8.7 ± 1.5	8.9 ± 2	9.8 ± 1.5	0.301
Hb (g/dL), mean ± SD	11.2 ± 1.4	11.2 ± 1.3	10.9 ± 1.4	12.2 ± 1.7	0.129
HCT (%), mean ± SD	34.1 ± 3.5	34.3 ± 3.3	34.2 ± 3.7	34.8 ± 4.9	0.861
ESRD etiology, N (%)					0.185
DM	10 (14.3)	7 (16.2)	3 (14.3)	0
HTN	18 (25.7)	9 (20.9)	7 (33.3)	2 (33.3)
ADPKD	2 (2.8)	0	2 (9.5)	0
Glomerulonephritis	2 (2.8)	2 (4.6)	0	0
Obstructive	8 (11.4)	6 (14.0)	2 (9.5)	0
Others	7 (10.0)	5 (11.6)	2 (9.5)	0
DM and HTN	23 (47.1)	14 (32.5)	5 (23.8)	4 (66.7)

ADPKD, autosomal dominant polycystic kidney disease; BMI, body mass index; BF, blood flow rate in dialysis; BUN, blood urea nitrogen; Cr, creatinine; CRP, C-reactive protein; cTnI, cardiac troponin I; DM, diabetes mellitus; ESR, erythrocyte sedimentation rate; ESRD, end-stage renal disease; Hb, hemoglobin; HCT, hematocrit; HTN, hypertension; IDH, intradialytic hypotension; MPV, mean platelet volume; PTH, parathyroid hormone; SD, standard deviation; UF, ultrafiltration rate.