Research Article

Association of Interleukin-17F Polymorphism and Mortality Predictors with the Risk of COVID-19

Table 2

Clinical, laboratory, and radiological data of the study COVID-19 patients (n = 132).

Variable n (%), median (25th–75th percentile)COVID-19 patients total (n = 132)Survivors (n = 75)Non-survivors (n = 57)P

Clinical data
 Temperature (°C)38 (37.6–38)38 (37.7–38)38 (37.5–38.6)0.527
 RR (breaths/minute)30 (26–36)28 (24–30)35 (30–39)<0.001
 Cough symptom score (CSS)2 (1–2)2 (1–2)2 (2–2)0.196
 Modified MRC Dyspnea Scale3 (3–4)3 (2–3)4 (3–4)<0.001

Clinical severity
 Noncritical38 (28.8)36 (48)2 (3.5)<0.001
 Critical94 (71.2)39 (52)55 (96.5)
 Duration of hospital stay (days)10 (7–14)8 (6–13)11 (8–14)0.028

Laboratory data
 Hemoglobin level (g/dl)11.3 (10.1–12.7)11.3 (10.1–12.4)11.3 (10–13)0.793
 Platelet (× 103 per mm3)231 (176.8–282.3)241 (179–269)224 (172.5–301.5)0.938
 WBCs (× 103 per mm3)8.9 (6.4–12.9)7.8 (6.6–11.1)11.6 (8.5–16.4)0.022
 Lymphocyte (× 103 per mm3)1.1 (0.8–1.5)1.2 (0.85–1.5)1 (0.7–1.5)0.157
 Neutrophil (× 103 per mm3)6.6 (4.8–11)5.8 (5.2–9.8)8.1 (4.4–14.2)0.055
 CRP (mg/L)96 (48–142.8)88 (40–123)110 (52.5–170.5)0.001
 D-dimer (ng/ml)0.8 (0.6–1.3)0.7 (0.45–0.9)1.2 (0.85–1.5)<0.001

Radiological data
 CT severity
  Mild to moderate38 (28.8)37 (49.3)1 (1.8)<0.001
  Severe94 (71.2)38 (50.7)56 (98.2)

IL-17F genotype
 C/T17 (12.9)11 (14.7)6 (10.5)0.482
 T/T-C/C115 (87.1)64 (85.3)51 (89.5)

CRP:C-reactive protein; CSS: cough symptom score (CSS); CT: computerized tomography MRC: modified medical research council; RR: respiratory rate, WBCs: white blood cells.