Research Article

Differences in Clinical and Imaging Features between Asymptomatic and Symptomatic COVID-19 Patients

Table 1

Clinical data of the patients [n (%)].

ItemsAsymptomatic carriersCOVID-19 patients (n = 36)
Remain asymptomatic (n = 25)Developed symptomatic (n = 22)

Gender0.640.73
 Male15 (60.0)15 (68.18)25 (69.44)
 Female10 (40.0)7 (31.82)11 (30.56)

Age12.420.02
 <18 years9 (36.0)1 (4.55)2 (5.56)
 18–50 years11 (44.0)14 (63.64)22 (61.11)
 ≥50 years5 (20.0)7 (31.82)12 (33.33)

Epidemic history52.32<0.001
 In Wuhan and surrounding areas0013 (37.14)
 Close contact25 (100.0)22 (100.0)12 (33.33)
 Unclear epidemic0010 (27.78)

Maximum body temperature1.470.72
 ≤37.2°C3 (13.64)3 (8.33)
 37.3–38°C7 (31.82)15 (41.67)
 38.1–38.9°C3 (13.64)10 (27.78)
 ≥39°C1 (4.55)3 (8.33)

Cough7 (31.82)16 (44.44)0.910.34

Expectoration3 (13.64)8 (22.22)0.660.51

Sore throat07 (19.44)4.870.03

Headache and dizziness1 (4.55)01.670.38

Fatigue7 (31.82)4 (11.11)3.810.08

Muscle ache2 (9.1)1 (2.78)1.110.55

Chest tightness and dyspnea1 (4.55)2 (5.56)0.031.00

Gastrointestinal reaction01 (2.78)0.621.00

Normal or decreased leukocyte count13 (52.0)22 (100.0)31 (86.11)18.25<0.001

Decreased lymphocyte count3 (12.0)6 (27.27)15 (41.67)6.360.04

Neutrophil/lymphocyte ratio2.03 ± 2.003.32 ± 1.434.32 ± 4.383.820.02

Increased C-reactive protein4 (16.0)16 (72.73)29 (80.56)27.75<0.001

Abnormal hepatic function2 (8.0)5 (22.73)19 (52.78)14.780.001

Abnormal renal function2 (8.0)5 (22.73)13 (36.11)6.410.04

Increased D-dimer3 (12.0)11 (50.0)4 (11.11)14.140.001

Abnormal myocardial enzymes6 (24.0)7 (31.82)16 (44.44)2.840.24

With comorbidities3 (12.0)1 (4.55)15 (41.67)13.060.001

Hospitalization days12.08 ± 5.5914.29 ± 5.8315.17 ± 7.051.790.17

No. of severe patients01 (4.55)4 (11.11)3.330.17

Note. Asymptomatic, those who remained asymptomatic; symptomatic, those who developed symptomatic later; VOCID-19, symptomatic COVID-19 patients. The Fisher exact test was used; #ANOVA was used.