Research Article

The Association between Energy-Adjusted Dietary Inflammatory Index, Body Composition, and Anthropometric Indices in COVID-19-Infected Patients: A Case-Control Study in Shiraz, Iran

Table 2

Characteristics of participants according to quartile of E-DII, COVID-19 case-control study nested within the Cohort Study of Shiraz University of Medical Sciences (SUMS), 2017–2021.

Variables1st quartile2nd quartile∗∗3rd quartile∗∗∗4th quartile∗∗∗∗ value

Gender, N (%)0.001
 Female78 (68.4)61 (53.5)52 (45.6)58 (51.3)
 Male36 (31.6)53 (46.5)62 (54.4)55 (48.7)
COVID-19, N (%)≤0.001
 Yes6 (5.3)18 (15.8)33 (28.9)76 (67.3)
 No108 (94.7)96 (84.2)81 (71.1)37 (32.7)
Smoking habits, N (%)0.57
 Nonsmoker100 (87.7)97 (85.1)93 (81.6)98 (80.7)
 Smoker14 (12.3)17 (14.9)21 (18.4)15 (13.3)
Age, (year), mean (SD)41.54 (6.72)40.75 (6.31)39.68 (6.32)39.97 (6.99)0.16
Weight, (kg), mean (SD)71.91 (12.88)73.95 (14.94)75.94 (13.95)73.02 (13.85)0.07
BMI, (kg/m2), mean (SD)26.84 (4.14)26.94 (4.11)27.12 (4.28)26.61 (4.22)0.74
Food parameters, mean (SD)
Vitamin A (μg/day)758.38 (828.96)792.26 (551.93)1013.27 (981.08)1062.02 (615.96)≤0.001
Βeta-carotene (μg/day)4195.05 (3751.54)3623.80 (3427.30)3346.71 (3190.90)1665.86 (1695.02)≤0.001
Vitamin D (μg/day)1.61 (1.16)1.65 (1.35)1.52 (1.88)1.43 (1.65)0.01
Vitamin E (mg/day)22.49 (11.18)23.86 (14.01)23.30 (13.80)26.34 (16.71)0.28
Vitamin C (mg/day)184.45 (112.36)196.3 (135.82)177.58 (99.82)181.61 (90.06)0.94
Thiamin, B1 (mg/day)2.67 (2.13)2.52 (1.06)2.41 (1.16)2.20 (0.65)0.23
Riboflavin, B2 (mg/day)2.75 (1.75)2.49 (1.11)2.36 (1.27)2.08 (0.70)0.001
Niacin, B3 (mg/day)28.95 (20.71)28.18 (10.45)26.96 (11.56)25.61 (7.36)0.37
Pyridoxine, B6 (mg/day)2.36 (1.52)2.36 (0.85)2.28 (0.93)2.17 (0.56)0.64
Folate, B9 (μg/day)734.36 (383.95)719.10 (293.84)640.19 (306.29)498.97 (204.57)≤0.001
Cobalamin, B12 (μg/day)4.13 (7.56)5.87 (2.46)4.01 (4.37)4.30 (3.17)0.28
MUFA (g/day)29.13 (14.50)28.83 (11.77)26.12 (11.31)26.19 (11.59)0.10
PUFA (g/day)22.96 (10.06)23.59 (10.96)22.62 (11.03)27.29 (13.45)0.01
Omega-6 (g/day)20.52 (9.37)21.15 (10.53)20.77 (10.62)24.41 (13.01)0.02
Omega-3 (g/day)1.03 (0.71)1.00 (0.68)0.81 (0.50)0.65 (0.46)≤0.001
Iron (mg/day)43.16 (42.28)39.77 (32.85)36.93 (32.51)25.78 (13.07)≤0.001
Zinc (mg/day)14.91 (10.22)13.27 (4.71)12.53 (4.91)11.64 (3.61)0.002
Magnesium (mg/day)512.65 (428.63)452.20 (170.55)423.79 (187.68)362.69 (120.01)≤0.001
Selenium (mg/day)134.30 (175.36)109.93 (69.03)89.27 (82.70)40.29 (63.13)≤0.001
Fiber (g/day)59.15 (46.81)60.99 (41.85)47.72 (26.17)31.55 (18.21)≤0.001
Total fat (g/day)79.49 (39.98)79.69 (28.67)74.44 (28.31)82.10 (29.33)0.23
Cholesterol (mg/day)245.29 (154.93)261.50 (137.20)240.39 (177.10)263.85 (116.31)0.03
Saturated fat (g/day)19.05 (15.30)19.07 (6.99)17.82 (7.12)18.97 (6.13)0.33
Trans-fat (g/day)00 (00)00 (00)00 (00)00 (00)0.43

Quartile 1 = ≤−2.76; Quartile 2 = −2.75 – (-) 1.65; Quartile 3 = −1.64 – (-) 0.55; Quartile 4 ≥ −0.54. ANOVA or Kruskal–Wallis test was used for continuous variables and Chi-square was used for categorical variables. E-DII: energy-adjusted dietary inflammatory index; BMI: body mass index; BFM: body fat mass; WHR: waist-to-hip ratio; FFM: fat-free mass; SMM: skeletal muscle mass; VFA: visceral fat area.