Research Article

A Comparison of the Efficacy of 5 mg Olanzapine and Aprepitant in the Prevention of Multiple-Day Cisplatin Chemotherapy-Induced Nausea and Vomiting

Table 2

Baseline characteristics of patients in two groups (n (%)).

CharacteristicsOlanzapine group (n = 104)Aprepitant group (n = 106)

Age (years)59.26 ± 8.86560.01 ± 10.3580.574
 ≥5579 (75.96)78 (73.58)0.692

Gender0.755
 Male64 (61.54)63 (59.43)
 Female40(38.46)43(40.57)

Smoking index0.474
 No smoking39 (37.50)47 (44.34)
 0∼40013 (12.50)9 (8.49)
 ≥40052 (50.00)50 (47.17)

Alcohol use0.725
 No consumption48 (46.15)50 (47.17)
 <4 drinks per week38 (36.54)34 (32.08)
 ≥4drinks per week18 (17.31)22 (20.75)

History of female pregnancy vomiting13 (32.5)11 (25.58)0.487

History of motion sickness17 (16.35)21 (19.81)0.514

Chemotherapy cycle0.232
 First cycle27 (25.96)37 (34.90)
 Second cycle30 (28.845)23 (21.70)
 Third cycle17 (16.35)23 (21.70)
 Fourth cycle30 (28.845)23 (21.70)

Type of malignancies0.755
 Lung cancer40 (38.46)43 (40.57)
 Others64 (61.54)63 (59.43)