Research Article
Relationship between Blood Lipid Profiles and Risk of Lupus Nephritis in Children
Table 1
Characteristics of the enrolled subjects.
| | Characteristics | LN group (N = 65) | Non-LN group (N = 69) | T, χ2 or Z | value |
| | Age, years | 10.23 ± 2.57 | 10.64 ± 2.53 | −0.923 | 0.358 | | Sex, no. (%) | | | 0.414 | 0.520 | | Male | 13 (20%) | 17 (24.6%) | | | | Female | 52 (80%) | 52 (75.4%) | | | | BMI (kg/m2) | 21.96 ± 7.91 | 20.73 ± 2.03 | 1.093 | 0.277 | | FBG (mmol/L) | 5.13 ± 0.75 | 4.93 ± 0.77 | 1.569 | 0.119 | | ESR (mm/h) | 36.31 ± 21.55 | 32.16 ± 25.17 | 0.993 | 0.323 | | C3 (g/L) | 0.26 ± 0.14 | 0.55 ± 0.28 | −7.615 | 0.001 | | C4 (g/L) | 0.04 ± 0.03 | 0.10 ± 0.07 | −6.154 | 0.001 | | Anti-dsDNA, no. (%) | | | 4.705 | 0.030 | | Positive | 50 (76.9%) | 41 (59.4%) | | | | Negative | 15 (23.1%) | 28 (40.6%) | | | | Anti-Sm, no. (%) | | | 3.350 | 0.067 | | Positive | 21 (32.3%) | 33 (47.8%) | | | | Negative | 44 (67.7%) | 36 (52.2%) | | | | SLEDAI score, no. (%) | | | −7.878 | 0.001 | | No activity (score: 0–4) | 1 (1.5%) | 30 (43.5%) | | | | Mild-to-moderate activity (score: 5–14) | 31 (47.7%) | 38 (55.1%) | | | | High activity (score: ≥ 15) | 33 (50.8%) | 1 (1.4%) | | | | Blood lipid profiles no. (%) | | | 5.632 | 0.018 | | Normal blood lipids | 7 (10.8%) | 20 (29.0%) | | | | Dyslipidemia | 58 (89.2%) | 49 (71.0%) | | |
|
|
BMI: body mass index; FBG: fasting blood glucose; ESR: erythrocyte sedimentation rate; C3/C4: C3/C4 complement; anti-dsDNA: anti-double-stranded DNA antibody; anti-Sm: anti-Smith antibody; SLEDAI: systemic lupus erythematosus disease activity index.
|
