Review Article

Efficacy of ω-3 Polyunsaturated Fatty Acids in Patients with Lung Cancer Undergoing Radiotherapy and Chemotherapy: A Meta-Analysis

Table 2

GRADE quality of evidence.

OutcomesNo. of studiesIntervention sample/control sampleCertainty assessmentCertainty
Risk of biasInconsistencyIndirectnessImprecisionOther considerations

Weight change6201/193SeriousSeriousNoneNot seriousNone⊕⊕〇〇 low
Albumin change275/75SeriousNot seriousNoneSeriousNone⊕⊕〇〇 low
Energy intake at the end of the intervention4108/109SeriousSeriousNoneSeriousSerious⊕〇〇〇 very low
Protein intake at the end of the intervention379/80SeriousNot seriousNoneNot seriousNone⊕⊕⊕〇 moderate
CRP change5173/157SeriousSeriousNoneSeriousSerious⊕〇〇〇 very low
TNF-α change4165/149SeriousSeriousNoneNot seriousNone⊕⊕〇〇 low

Note: evidence level downgrades one level when marked as serious.