Research Article

Assessment of Patients’ Views on Drug Benefits and Risks: An Interview Study with Cardiovascular Patients

Table 2

Frequencies of whether a mentioned risk was perceived as bothersome, concerning, or led the patients to take their medication differently than prescribed. Percentages are based on the total number of mentions of the respective risk.

Reported riskTotal mentions of risk nRisk perceived as bothersome n (n (%))Risk perceived as concerning n (n (%))Risk resulting in taking medication differently than prescribed n (n (%))

Gastrointestinal disorders without mouth and throat complaints9554 (57%)30 (32%)12 (13%)
Mouth and throat complaints5633 (59%)13 (23%)1 (2%)
Cardiac disorders/hypertension/hypotension4420 (45%)19 (43%)2 (5%)
Skin and subcutaneous tissue disorders4020 (50%)12 (30%)2 (5%)
Psychiatric disorders3820 (53%)21 (55%)2 (5%)
Urinary urgency3218 (56%)7 (22%)10 (31%)
Increased bleeding tendency (i.a. INR increased)/hematoma/epistaxis2812 (43%)7 (25%)2 (7%)
Eye disorders2414 (58%)10 (42%)1 (4%)
Fatigue2215 (68%)7 (32%)0 (0%)
Cough/dyspnea2118 (86%)10 (48%)2 (10%)
Dizziness1912 (63%)6 (32%)1 (5%)
Localized edema1813 (72%)9 (50%)1 (6%)
Renal and urinary disorders without urinary urgency165 (31%)10 (63%)1 (6%)
Anorexia/weight loss134 (31%)3 (23%)0 (0%)
Weight gain1312 (92%)4 (31%)0 (0%)
Nervous system disorders without dizziness139 (69%)4 (31%)0 (0%)
Myalgia/muscle cramp129 (75%)5 (42%)2 (17%)
Erectile dysfunction105 (50%)2 (20%)0 (0%)
Arthralgia/bone pain/osteoporosis84 (50%)4 (50%)0 (0%)
Hot flashes/flushing88 (100%)2 (25%)0 (0%)
Hepatobiliary disorders80 (0%)6 (75%)0 (0%)
Tinnitus64 (67%)3 (50%)0 (0%)
Neoplasms: benign, malignant, and unspecified (incl. cysts and polyps)50 (0%)2 (40%)0 (0%)
Allergic reaction/anaphylaxis42 (50%)3 (75%)0 (0%)
Hyperglycemia/hypoglycaemia41 (25%)0 (0%)0 (0%)
Influencing drug efficacy31 (33%)1 (33%)1 (33%)
Others157 (47%)4 (27%)1 (7%)