Research Article

Time Trends and Treatment Pathways in Prescribing Individual Oral Anticoagulants in Patients with Nonvalvular Atrial Fibrillation: An Observational Study of More than Three Million Patients from Europe and the United States

Table 2

Basic description of the AF study cohorts.

Data sourcePatients (N)Mean age (±SD) at first OAC prescription% female

Belgium LPD654674.5 (10.5)45
France DA505373.6 (10.5)43
Germany DA72,29774.1 (10.1)47
UK THIN52,72074.1(10.5)44
UK CPRD48,83074.3 (10.5)44
US LRxDx3,195,57870.3 (10.5)45
US PMTX193,11863.1 (11.0)35
US Marketscan CCAE97,22056.2 (7.1)31
US Marketscan MDCR170,97178.0 (7.3)47

Some patients could potentially contribute to more than one database, for example, THIN and CPRD databases in the UK. AF: atrial fibrillation; CCAE: Commercial Claims and Encounters; CPRD: Clinical Practice Research Datalink; DA: Disease Analyzer; IMRD: IQVIA Medical Research Data UK; LPD: Longitudinal Patient Database; LRxDx: Longitudinal Prescription Diagnosis database; MDCR: Medicare Supplemental and Coordination of Benefits; OAC: oral anticoagulant; PMTX: Pharmetrics; SD: standard deviation.