Research Article

Hospital-Acquired Acute Kidney Injury in Noncritical Care Setting: Clinical Characteristics and Outcomes

Table 2

Baseline characteristics of study population at the time of AKI (n = 222).

CharacteristicsAll patientsNephrology consultation(n = 31)No nephrology consultation (n = 191)

Age (mean (SD)) years74.8 (15.8)71.81 (16.8)75.28 (15.66)
 Median (IQR)77 (68–86)77 (58–86)77 (69–86)0.339
Gender
 Male (N (%))95 (42.8)12 (38.7)83 (43.5)0.698
Hospitalisation
 Medical specialty (N (%))194 (87.4)28 (90.3)166 (86.9)0.774
 Surgical specialty (N (%))28 (12.6)3 (9.7)25 (13.1)
Time of hospital admission to AKI (mean (SD)) days2.5 (1.6)2.5 (1.9)2.5 (1.6)
 Median (IQR)2 (1–3)2 (1–3)2 (1–3)0.695
Surgical procedures during hospitalisation
 Yes (N (%))36 (16.2)4 (13)32 (18)0.566
Charlson’s comorbidity score (mean (SD))3.82 (2.4)3.1 (2.7)3.9 (2.3)
 Median (IQR)4 (2–5)3 (2–5)4 (2–5)0.322
Number of medical conditions (mean (SD))7.2 (3.9)7.3 (4.9)7.1 (3.7)
 Median (IQR)7 (4–10)7 (4–10)7 (4–10)0.742
Number of medications (mean (SD))7 (4.4)5.1 (4.2)7.32 (4.4)
 Median (IQR)7 (4–10)5 (1–8)7 (4–11)0.009
Risk factors for AKI (N (%))
 Hypertension164 (73.9)23 (74.2)141 (73.8)1
 Age >75 years126 (56.8)18 (58.1)108 (56.5)1
 Nephrotoxic medications120 (54.1)16 (51.6)104 (54.5)0.847
 Diabetes90 (40.5)9 (29)81 (42.4)0.174
 Contrast47 (21.2)11 (35.5)36 (18.8)0.055
 Preexisting kidney dysfunction35 (15.8)8 (25.8)27 (14.1)0.112
 Renal artery stenosis10 (4.5)3 (9.7)7 (3.7)0.149

Nephrology consultation also includes patients admitted under renal medicine specialty; angiotensin agents, i.e., angiotensin-converting enzyme inhibitors and angiotensin receptor blockers, aminoglycosides, vancomycin, and nonsteroidal anti-inflammatory drugs.