The Distribution of Cytotoxic Necrotizing Factors (CNF-1, CNF-2, CNF-3) and Cytolethal Distending Toxins (CDT-1, CDT-2, CDT-3, CDT-4) in Escherichia coli Isolates Isolated from Extraintestinal Infections and the Determination of their Phylogenetic Relationship by PFGE

Table 3

The distribution of toxin genes in 646 ExPEC isolates.

VFs (%)	All isolates (n = 646) n (%)	Urinary system n = 522 (80)	Nonurinary system
			Total n = 124 (20)	Wound (n = 54)	Blood (n = 28)	Sputum (n = 21)	Aspirate (n = 6)	Sterile body fluid (n = 12)	Vagen (n = 3)
cnf1	78 (12)	68 (13)	10 (8)	3 (5)	3 (11)	3 (14)	1 (16)	—	—
cnf2	12 (2)	10 (2)	2 (1, 6)	1 (2)	1 (4)	—	—	—	—
cnf3	20 (3)	16 (3)	4 (2, 3)	2 (4)	1 (4)	1 (5)	—	—	—
cnf1–cnf3	6 (0, 9)	5 (1)	1 (0,8)	—	1 (4)	—	—	—	—
Total cnfs	116 (18)	99 (20)	17(13)
cdt1	20 (3)	12 (2)	8 (7)	—	2 (8)	2 (10)	2 (31)	2 (16)	—
cdt2	4 (0,6)	2 (0,3)	2 (1, 7)	1 (2)	1 (4)	—	—	—	—
cdt3	4 (0,6)	2 (0,3)	2 (1, 7)	—	—	1 (5)	—	—	—
cdt4	4 (0,6)	2 (0,3)	2 (1, 7)	1 (2)	—	—	1 (16)	—	—
cdt1–cdt4	4 (0,6)	1 (0,2)	3 (2, 3)	2 (4)	1 (4)	—	1 (16)	—	—
Total cdts	36 (4, 5)	19 (3, 6)	17 (13.7)
cnf1-cdt1	4 (0,9)	3 (0,8)	1 (1, 7)	1 (2)	—	—	—	—	—