The Effect of Ondansetron on the Analgesic Efficacy of Tramadol in Patients Undergoing Laparoscopic Cholecystectomy

Table 3

Incidence of postoperative nausea, vomiting, the use of rescue antiemetic, and complete response in both groups.

	Group O (n = 28)	Group S (n = 27)	value
Nausea (NRS > 4)
0–1 h	8 (28%)	6 (22%)	0.547 (2)
1–2 h	0 (0%)	3 (11%)	0.111 (2)
2–4 h	1 (3%)	1 (3%)	1.0 (2)
4–8 h	2 (7%)	3 (11%)	1.0 (2)
8–12 h	2 (7%)	4 (14%)	0.729 (2)
12–24 h	1 (3%)	1 (3%)	1.0 (2)
0–24 h	10 (35%)	12 (44%)	0.789 (2)
Vomiting
0–1 h	0 (0%)	0 (0%)	—
1–2 h	0 (0%)	0 (0%)	—
2–4 h	0 (0%)	0 (0%)	—
4–8 h	1 (3%)	5 (18%)	0.101 (2)
8–12 h	0 (0%)	2 (7%)	0.111 (2)
12–24 h	0 (0%)	1 (3%)	0.491 (2)
0–24 h	1(3%)	7 (26%)	0.78 (2)
Rescue antiemetic
0–1 h	8 (28%)	6 (22%)	0.758 (2)
1–2 h	0 (0%)	3 (11%)	0.111 (2)
2–4 h	1 (3%)	1 (3%)	1.0 (2)
4–8 h	3 (10%)	5 (18%)	0.469 (2)
8–12 h	2 (7%)	7 (26%)	0.078 (2)
12–24 h	2 (7%)	3 (11%)	0.669 (2)
0–24 h	10 (35%)	14 (51%)	0.423 (2)
Complete response
0–1 h	20 (71%)	21(77%)	0.758 (2)
1–2 h	28 (100%)	24 (88%)	0.111 (2)
2–4 h	27 (96%)	26 (96%)	1.0 (2)
4–8 h	25 (89%)	22 (81%)	0.469 (2)
8–12	26 (92%)	20 (74%)	0.078 (2)
12–24 h	26 (92%)	24 (88%)	0.669 (2)
0–24 h	18 (64%)	13 (48%)	0.282 (2)

Group O: ondansetron group; Group S: saline group; NRS: numeric rating scale (2): Fisher’s exact test.