The Effect of Ondansetron on the Analgesic Efficacy of Tramadol in Patients Undergoing Laparoscopic Cholecystectomy

Table 4

Comparison on NRS pain and nausea score during postoperative 24 h in both groups.

	Group O (n = 28), mean ± SD	Group S (n = 27), mean ± SD	Mean difference (95% CI) (group O–S)
NRS pain score
0-1 h	4.21 ± 2.71	3.14 ± 2.90	1.06 (−0.45, 2.58)
1–2 h	2.85 ± 2.06	2.85 ± 2.01	0.00 (−1.09, 1.10)
2–4 h	2.17 ± 1.88	2.33 ± 1.92	−0.15 (−1.18, 0.87)
4–8 h	1.89 ± 1.89	2.00 ± 1.96	−0.10 (−1.14, 0.93)
8–12 h	1.60 ± 1.49	1.48 ± 1.31	0.12 (−0.63, 0.88)
12–24 h	1.32 ± 1.86	1.07 ± 1.61	0.24 (−0.69, 1.19)
NRS nausea score
0–1 h	1.75 ± 2.88	1.48 ± 2.56	0.26 (−1.21, 1.74)
1–2 h	0.46 ± 1.03	1.07 ± 2.03	−0.60 (−1.47, 0.25)
2–4 h	0.25 ± 0.96	0.48 ± 1.36	−0.23 (−0.87, 0.40)
4–8 h	0.50 ± 1.62	0.85 ± 2.26	−0.35 (−1.41, 0.71)
8–12 h	0.42 ± 1.34	1.40 ± 3.01	−0.97 (−2.23, 0.27)
12–24 h	0.32 ± 1.36	0.40 ± 1.24	−0.08 (−0.79, 0.62)

Group O: ondansetron group; Group S: saline group; NRS: numeric rating scale; SD: standard deviation; CI: confidence interval.