Minor Salivary Gland Surgery and Histopathological Scoring System: A Systematic Review

Table 4

2016 classification criteria for primary SS by ACR/EULAR [13].

Item	Weight/score
Labial salivary gland with focal lymphocytic sialadenitis and focus score of ≥ 1 foci/4 mm^2	3
Anti-SS-A/anti-Ro positive	3
Ocular staining score (OSS) ≥ 5 (or van bijsterveld score (vBS) ≥ 4) in at least one eye	1
Schirmer’s test ≤ 5 mm/5 min in at least one eye	1
Unstimulated whole saliva flow rate ≤ 0.1 ml/min	1

Individuals with signs and/or symptoms suggestive of SS who have a total score of ≥ 4 for the above items meet the criteria for primary SS. Inclusions: symptoms of oral or ocular dryness or 1 extraglandular manifestation of SS. Exclusions: history of head/neck irradiation, active hepatitis C (+PCR), HIV, sarcoidosis, amyloidosis, graft versus host disease, IgG4 syndrome.