Eosinophil Levels, Neutrophil-Lymphocyte Ratio, and Platelet-Lymphocyte Ratio in the Cytokine Storm Period of Patients with COVID-19

Table 1

Demographic, clinical data, and laboratory findings of COVID-19 patients with and without cytokine storm.

Parameters	CS (n = 76)	No CS (n = 150)	value
Age (years)	62.7 ± 1.3	49 ± 1.6	0.001
Number of females	20 (26.3%)	70 (48.7%)	0.001
COPD, n (%)	2 (2.6%)	1 (0.7%)	0.22
DM, n (%)	24 (31.6)	14 (9.3)	0.001
CAD, n (%)	25 (32.9)	8 (5.3)	0.001
SpO2 (%)	92 (74–98)	96 (75–98)	0.001
Clinic stay (day)	4 (0–33)	9 (0–40)	0.001
ICU stay (day)	15 (0–65)	3.2 (0–61)	0.001
Death, n (%)	48 (63.2%)	17 (11.3%)	0.001
Neutrophil, 10^3/L	8.1 (1.7–38)	4.06 (0.37–22)	0.001
Lymphocyte, 10^3/L	0.68 (0.14–9.5)	1.43 (0.39–9.8)	0.001
Monocyte. 10^3/L	0.37 (0.01–1.231)	0.51 (0.14–1.44)	0.001
Eosinophil, 10^3/L	0.00 (0–0.55)	0.02 (0–1.45)	0.001
PLT, 10^3/L	275 (33–824)	222 (96–623)	0.001
RDW-SD, fL	42 (33–76)	39 (30–66)	0.001
PDW, fL	11.9 ± 1.9	12.1 ± 2.04	0.6
D-Dimer, ug FEU/ml	1.8 (0.32–19)	0.42 (0.15–16)	0.001
Ferritin, ng/mL	968 (140–2898)	265 (8.2–1941)	0.001
IL-6, pg/mL	663 (38–24512)	48 (8–691)	0.001
CRP, mg/L	116 (0.9–372)	18 (0.3–434)	0.001
NLR	11 (0.53–72)	2.5 (0.44–25)	0.001
PLR	408 (29–3021)	151 (27–714)	0.001
MLR	0.52 (0.03–2.09)	0.36 (0.1–1.6)	0.001

COPD, chronic obstructive pulmonary disease; DM, diabetes mellitus; CAD, coronary artery disease; SpO₂, the percent saturation of oxygen in blood; ICU, intensive care unit; PLT, platelets; IL-6, interleukin-6; NLR, neutrophil-lymphocyte ratio; PLR, platelet-lymphocyte ratio; MLR, monocyte-lymphocyte ratio. , statistically significant.