Postchemoradiotherapy Neutrophil-to-Lymphocyte Ratio Predicts Distant Metastasis and Survival Results in Locally Advanced Pancreatic Cancers

Table 2

Outcomes of uni- and multivariate analysis.

Characteristics	Overall survival			Distant metastasis-free survival
	Univariate	Multivariate	HR	Univariate	Multivariate	HR
	value	value		value	value
Age group (<70 vs. ≥70 years)	0.93	—	—	0.78	—	—
Gender (female vs. male)	0.79	—	—	0.72	—	—
ECOG (0 vs.1)	0.90	—	—	0.83	—	—
Tumor location (H vs. B/T)	0.64	—	—	0.76	—	—
Tumor size (<vs. ≥3.7 mm)	0.41	—	—	0.48	—	—
LN status (N0 vs. N1-2)	0.007	0.005	1.72	<0.001	<0.001	2.16
CA 19–9 (<vs. ≥90 U/mL)	0.001	0.002	1.94	0.001	0.001	2.04
NLR (<vs. ≥3.1)	<0.001	<0.001	3.72	<0.001	<0.001	5.68

Abbreviations. HR: hazard ratio; ECOG: Eastern Cooperative Oncology Group; H: head; B/H: body/tail; NX: nodal stage x; CA 19–9: cancer antigen 19–9; NLR: neutrophil-to-lymphocyte ratio.