Research Article

Long-Term Adherence and Persistence to Low-Dose Aspirin for the Prevention of Cardiovascular Disease: A Population-Based Cohort Study

Table 1

Demographics and median observation time of the study cohorts.

Data sourceCohortNMean age (SD), years% femaleMedian observation time (IQR), years

IQVIA Germany disease analyzerPrimary CVD prevention43,01369.5 (12.7)514.3 (2.4–6.8)
Secondary CVD prevention101,70469.0 (12.3)424.1 (2.4–6.5)
Secondary CVD prevention DAPT23,07365.3 (12.3)324.0 (2.4–6.2)

IMRD UKPrimary CVD prevention72,49665.0 (15.2)494.8 (2.8–7.3)
Secondary CVD prevention118,41165.5 (13.1)454.4 (2.6–6.8)
Secondary CVD prevention DAPT27,64863.1 (12.7)314.1 (2.4–6.3)

From the date of the first low-dose aspirin prescription (index date). Started on DAPT. Abbreviations: CVD, cardiovascular disease; DAPT, dual antiplatelet therapy; IMRD, IQVIA Medical Research Data; IQR, inter-quartile range; SD, standard deviation.