Association between Gut Microbiota Dysbiosis and the CHA2DS2-VASc Score in Atrial Fibrillation Patients

Figure 3

Prediction score of thromboembolic risk in AF patients. (a, b) The most predictive tax of GM and KOs were presented, including 20 species and 22 KOs. (a) The heatmap shows the relative abundance (log 10) of 20 species (all ). (b) The fold change (log 2) in the relative abundance of 22 KOs. (c) Correlations between 20 species and 22 KOs. Pearson’s correlation coefficients were calculated. Red, positive correlation; blue, negative correlation. (d) ROC curve showed the relevant predictive value of the KO score, AUC = 0.993, 95% CI: 0.916–1.000, . (e) Mediation analysis on microbial diversity (Shannon index and Pielou’s evenness), KO scores, LAVI, and thromboembolic risk of AF patients. VAF = 11.1%, . ; ; .

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