Incidence and Complications of Atrial Fibrillation in a Low Socioeconomic and High Disability United States (US) Population: A Combined Statistical and Machine Learning Approach

Table 3

Odds ratios “OR” (95% CI) for relationships between baseline characteristics of comorbid history/demographic variables/Medicaid group categories and atrial fibrillation status group as an outcome, with cost threshold (of ^$2000 or more in the year prior to index date or the equivalent for non-AF cases) as a model feature.

Variable	Level	OR	95% CL
Congestive heart failure	1 vs 0	2.38	2.24	2.53
Hypertension	1 vs 0	1.56	1.48	1.64
Diabetes mellitus	1 vs 0	1.18	1.12	1.24
Stroke	1 vs 0	1.30	1.21	1.40
Vascular disease	1 vs 0	1.21	1.14	1.29
Valvular disease	1 vs 0	1.62	1.52	1.73
Coronary artery disease	1 vs 0	1.36	1.28	1.44
Chronic sleep apnea	1 vs 0	1.16	1.04	1.29
Chronic kidney disease	1 vs 0	1.36	1.28	1.45
Chronic pulmonary obstructive disease/bronchiectasis	1 vs 0	1.53	1.46	1.61
Major bleeding	1 vs 0	1.20	1.12	1.28
Cognitive impairment	1 vs 0
Liver disease	1 vs 0	1.17	1.10	1.24
Anemia	1 vs 0	1.29	1.23	1.36
Depression	1 vs 0	1.19	1.13	1.24
Lipid disorders	1 vs 0	0.93	0.89	0.97
Spondylosis and intervertebral discs	1 vs 0	1.13	1.08	1.18
Osteoarthritis	1 vs 0	1.09	1.04	1.15
Hyperthyroidism	1 vs 0	1.24	1.06	1.44
Metabolic syndrome	1 vs 0	0.58	0.43	0.77
Asthma	1 vs 0	0.70	0.65	0.75
Gender	1 vs 0	0.74	0.71	0.77
Age group	4 vs 0	7.01	6.41	7.66
	3 vs 0	4.17	3.82	4.56
	2 vs 0	2.28	2.14	2.44
	1 vs 0	1.72	1.61	1.83
Medicaid group	6 vs 0	1.62	1.48	1.78
	5 vs 0	2.43	2.24	2.65
	4 vs 0	1.28	1.16	1.40
	3 vs 0	1.54	1.44	1.65
	2 vs 0	1.55	1.45	1.65
	1 vs 0	3.22	2.93	3.52
Cost threshold (1 year prior)		1.62	1.54	1.71

Note: 1—The presence of comorbid condition; 0—the absence of comorbid condition; 75–90 (4) vs 18–44 years (0); 65–74 (3) vs 18–44 years (0); 55–64 (2) vs 18–44 years (0); 45–54 (1) vs 18–44 years (0); LTSS—duals (6) vs TANF (0); ABD—duals (5) vs TANF (0); LTSS—nondual (4) vs TANF (0); ABD—nondual (3) vs TANF (0); two groups (2) vs TANF (0); family care (1) vs TANF (0); model feature based on cost threshold of 1 year prior for ^$2000 or more (1 or > ^$2000; 0 otherwise); TANF group (1 or > $8750 that is applied for AF cohort only; 0 otherwise); 0—absence of comorbid condition, CL—confidence limits, and C index = 0.822. Data are based on the entire population.