The Association of Flow-Mediated Dilatation and Blood Parameters in Primary Raynaud’s Phenomenon
Table 1
Comparison of demographic and laboratory variables in pRP and healthy control groups.
Variables
Control (N: 30)
Raynaud’s phenomenon (N: 43)
p#
Female, n (%)
22 (73%)
34 (79%)
0.772
Age (mean ± SD)
27.17 ± 8.01
28.33 ± 8.71
0.565
Smoking, n (%)
8 (27%)
19 (44%)
0.201
Abnormal FMD, n (%)
5 (17%)
30 (70%)
0.001
WBC (10−3/μL)
6.20 ± 1.43
7.64 ± 1.73
0.001
Hemoglobin (g/dL)
13.46 ± 1.06
12.93 ± 1.78
0.148
Platelet count (10−3/μL)
225.50 ± 79.23
250.91 ± 74.67
0.167
MPV (fL)
8.36 ± 0.96
10.47 ± 0.87
0.001
Creatinine (mg/dL)
0.85 ± 0.17
0.79 ± 0.21
0.232
AST (IU/L)
21.20 ± 5.14
25.60 ± 9.77
0.027
ALT (IU/L)
23.45 ± 7.36
26.12 ± 12.94
0.311
D-dimer (%)
1.25 ± 1.15
2.50 ± 5.049
0.185
Fibrinogen (μg/ml)
258.94 ± 89.74
375.57 ± 160.49
0.001
FAR (%)
88.38 ± 66.85
112.54 ± 45.49
0.090
NLR (%)
9.44 ± 11.26
8.07 ± 6.03
0.501
Albumin (g/dL)
3.3500 ± 0.38841
3.3279 ± 0.70561
0.579
DDAR (%)
0.3819 ± 0.37301
0.9210 ± 1.65428
0.877
MCP-1 (pg/ml)
264.4342 ± 71.12647
332.4933 ± 39.45015
0.001
FMD: flow-mediated dilatation; WBC: white blood cell; MPV: main platelet volume; AST: aspartate aminotransferase; ALT: alanine aminotransferase; FAR: fibrinogen-to-albumin ratio; NLR: neutrophil-to-lymphocyte ratio; DDAR: D-dimer-to-albumin ratio; MCP-1: monocyte chemoattractant protein-1. is considered as statistically significant. The bold numbers show the p values below 0.05.
