Blood Urea Nitrogen for Short-Term Prognosis in Patients with Cardiogenic Shock Complicating Acute Myocardial Infarction

Table 3

Predictors for 30-day mortality and 30-day MACE by univariate and multivariate Cox analysis.

Predictors for 30-day mortality	Univariate analysis		Multivariate analysis
	HR (95%CI)	value	HR (95%CI)	value
Age, per 1-year increase	1.05 (1.03–1.06)	<0.001	1.03 (1.01–1.05)	0.009
Male	0.62 (0.42–0.92)	0.02
SBP, per mmHg increase	0.98 (0.97–0.99)	0.03	0.98 (0.97–1.00)	0.01
Lac >4.2 mmol/L	4.33 (2.87–6.56)	<0.001	2.59 (1.66–4.04)	<0.001
BNP >400 pg/mL	3.83 (2.37–6.19)	<0.001	1.99 (1.17–3.37)	0.01
BUN (continuous)	1.06 (1.04–1.08)	<0.001
BUN >8.95 mmol/L	4.09 (2.69–6.22)	<0.001	2.08 (1.28–3.36)	0.003
GFR ≤55 mL/min/1.73 m^2	3.53 (2.23–5.57)	<0.001
LVEF ≤50%	2.64 (1.75–4.00)	<0.001	1.73 (1.11–2.69)	0.02
Predictors for 30-day MACE	Univariate analysis		Multivariate analysis
	HR (95%CI)	value	HR (95%CI)	value
Age, per 1-year increase	1.02 (1.01–1.04)	0.001	1.02 (1.00–1.03)	0.04
Male	0.88 (0.63–1.24)	0.47
Lac >4.2 mmol/L	3.23 (2.30–4.53)	<0.001	2.69 (1.89–3.82)	<0.001
BNP >400 pg/mL	1.89 (1.35–2.66)	<0.001
BUN (continuous)	1.04 (1.02–1.06)	<0.001
BUN >8.95 mmol/L	2.63 (1.88–3.69)	<0.001	1.85 (1.29–2.66)	0.001
GFR ≤55 mL/min/1.73 m^2	2.17 (1.53–3.08)	<0.001
LVEF ≤50%	1.80 (1.28–2.51)	0.001

SBP: systolic blood pressure, Lac: lactate, TNI: cardiac troponin I, BNP: brain natriuretic peptide, BUN: blood urea nitrogen, GFR: glomerular filtration rate, and LVEF: left ventricular ejection fraction.