Research Article

The Relationship of Conduction Disorder and Prognosis in Patients with Acute Coronary Syndrome

Table 1

Baseline characteristics and clinical outcomes in the patients with and without conduction disorder.

With conduction disorderWithout conduction disorder-Value

Number general demographics339230578
 Age (years)69 (13.6)66 (13.8)<0.001
 Male sex (%)2412 (71.11)21088 (68.96)0.010
 BMI (kg/m2)24.84 (4.38)25.04 (4.39)0.024

Comorbidities
 Diabetes mellitus (%)1279 (37.71)11079 (36.23)0.090
 Hypertension (%)1939 (57.16)17089 (55.89)0.155
 PAOD (%)47 (1.39)213 (0.70)<0.001
 COPD (%)214 (6.31)1511 (4.94)<0.001
 ESRD (%)480 (14.15)2425 (7.93)<0.001
 Smoking (%)387 (11.41)4590 (15.01)<0.001
 Liver cirrhosis (%)44 (1.30)486 (4.59)0.193
 Prior GI bleeding (%)407 (12.00)3180 (10.40)0.004
 Prior stroke (%)227 (6.69)2085 (6.82)0.782
 HF (%)1118 (32.96)7097 (23.21)<0.001
 Valvular heart disease (%)159 (5.99)1815 (8.13)<0.001

Medication
 Antiplatelet agent
  Aspirin (%)2032 (59.91)19709 (64.45)<0.001
  Clopidogrel (%)1596 (47.05)15684 (51.29)<0.001
  Ticagrelor (%)556 (16.39)4381 (14.33)0.001
  Prasugrel (%)16 (0.47)145 (0.47)0.984
 ACEI/ARB/Entresto (%)1727 (50.91)15972 (52.23)0.144
β-blocker (%)1890 (55.72)17340 (56.71)0.271
 Diuretic (%)864 (25.47)5948 (19.45)<0.001
 Lipid-lowering agents (%)1784 (52.59)16329 (53.40)0.372

Left ventricular performance
 Mean LVEF (%)44.64 (20.73)49.85 (20.63)<0.001

F/U period (years)1.8 (1.5)2.9 (2.6)<0.001

Data are expressed as mean (standard deviation) or as number (percentage). Abbreviation: BMI: body mass index; PAOD: peripheral arterial occlusive disease; COPD: chronic obstructive pulmonary disease; ESRD: end-stage renal disease; GI: gastrointestinal; HF: heart failure; ACEI: angiotensin-converting enzyme inhibitor; ARB: angiotensin receptor blocker; MRA: mineralocorticoid receptor antagonist; LVEF: left ventricular ejection fraction; F/U: follow-up.