Esketamine Combined with Propofol TCI versus Propofol TCI for Deep Sedation during Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration: A Prospective, Randomized, and Controlled Trial
Table 3
Primary and secondary outcomes.
Group E (n = 68)
Group P (n = 67)
value
Primary outcome
Lidocaine dosage (ml/h)
4.36 (2.67–6.00)
6.0 0 (4.36–7.20)
Frequency of spraying (times/h)
2.18 (1.33–3.00)
3.00 (2.18–3.60)
Secondary outcome
Cough score
2 (0–4)
3 (2–4)
Propofol dosage (mg·kg−1·h−1)
3.47 (3.07–3.97)
4.27 (3.68–4.99)
Endoscopist satisfaction
10 (9–10)
10 (9–10)
Patient satisfaction
10 (10–10)
10 (10–10)
Recovery time (min)
6 (6–7)
6 (5–7)
Sedation-related adverse events (n, %)
Hypoxemia
4 (5.9)
8 (11.9)
RR < 7 (times/min)
3 (4.4)
4 (6.0)
Hypotension
11 (16.2)
14 (20.9)
Hypertension
3 (4.4)
4 (6.0)
Tachycardia
2 (2.9)
5 (7.5)
Bradycardia
1 (1.5)
0 (0)
Malignant arrhythmia
0 (0)
3 (4.5)
Laryngospasm
1 (1.5)
0 (0)
Hallucination
1 (1.5)
0 (0)
Nausea and vomiting
8 (11.8)
5 (7.5)
Data are expressed as median (interquartile range) or n (%). VAS, visual analogue scale; RR, respiratory rate. .
