Noninvasive Mechanical Ventilation in Patients with Viral Pneumonia-Associated Acute Respiratory Distress Syndrome: An Observational Retrospective Study

Table 1

Demographic and clinical characteristics of 45 patients with influenza A-associated acute respiratory distress syndrome.

	NIV success (n = 24)	NIV failure (n = 21)	value
Patient characteristics
Age (years)	57.9 ± 17.0	54.1 ± 14.0	0.427
Male gender	20 (83.3%)	16 (76.1%)	0.713
BMI (kg/m^−2)	25.5 ± 2.5	25.6 ± 3.5	0.845
Underlying diseases
Diabetes	1 (4.1%)	5 (23.8%)	0.083^a
Hypertension	8 (33.3%)	9 (42.8%)	0.552
Chronic obstructive pulmonary disease (COPD)	1 (4.1%)	0 (0.0%)	1.000^a
Coronary heart disease	3 (12.5%)	1 (4.7%)	0.611^a
Lower limbs varicosity	2 (8.3%)	0 (0.0%)	0.491^a
Schizophrenia	1 (4.1%)	1 (4.7%)	1.000^a
Renal calculus	2 (8.3%)	0 (0.0%)	0.491^a
Hepatocirrhosis	1 (4.1%)	0 (0.0%)	1.000^a
Parkinson’s disease	1 (4.1%)	0 (0.0%)	1.000^a
Tricuspid valve replacement (TVR)	1 (4.1%)	0 (0.0%)	1.000^a
Types of influenza viral
H7N9	6 (25.0%)	12 (57.1%)	0.037
H1N1	18 (75.0%)	9 (42.8%)	—
Disease score
APACHEII	16.8 ± 3.9	29.6 ± 9.2	<0.001
SOFA	4.0 ± 1.3	8.5 ± 3.7	<0.001
Murray	2.8 ± 0.5	3.7 ± 0.3	<0.001

Note. APACHE II = acute physiology and chronic health evaluation II; SOFA = sequential organ failure assessment. ^aCalculated using Fischer’s exact test.