Quality of Life, Procedural Success, and Clinical Outcomes following Transcatheter Mitral Valve Repair

Table 3

Univariable and multivariable cox regression analyses for the primary outcome at 1 year.

	Univariables		Multivariables
	HR (95% CI)	values	HR (95% CI)	values
30 days KCCQ score	0.97 (0.97–0.98)	<0.001	0.98 (0.97–0.99)	0.006
Baseline KCCQ (before the procedure)	0.98 (0.97–0.99)	<0.001	1.002 (0.99–1.01)	0.76
Age (continuous)	1.008 (0.98–1.03)	0.38	1.005 (0.97–1.03)	0.71
Female	1.13 (0.74–1.7)	0.56
Prior MI	2.3 (1.5–3.7)	<0.001	1.28 (0.63–2.5)	0.48
LVEF (continuous)	0.9 (0.97–0.99)	0.004	1.003 (0.97–1.03)	0.82
Residual MR ≥ moderate (TEE)	2.15 (1.2–3.7)	0.006	1.53 (0.71–3.2)	0.26
LVESD (continuous)	1.1 (1.004–1.35)	0.044	1.16 (0.81–1.65)	0.40
LVEDD (continuous)	1.1 (0.9–1.3)	0.33
STS risk score (MV repair)	1.047 (1.025–1.069)	<0.001	1.036 (1.001–1.071)	0.044
Functional MR	1.75 (1.14–2.7)	0.01	1.5 (0.76–2.9)	0.24
Creatinine (continuous)	1.2 (1.1–1.3)	<0.001	1.17 (0.99–1.3)	0.057
V wave postprocedure	1.0 (0.99–1.01)	0.13
BNP (continuous)	1.00 (1.00–1.01)	0.003	1.00 (1.00–1.00)	0.84
TR ≥ moderate	1.61 (1.04–2.5)	0.031	1.4 (0.77–2.5)	0.26

MI-myocardial infarction, LVEF-left ventricular ejection fraction, LVESD-left ventricular end-systolic diameter, LVEDD-left ventricular end-diastolic diameter, BNP-brain natriuretic peptide, TR-tricuspid regurgitation.