International Journal of Clinical Practice

Research Article

The Possible Mediatory Role of Inflammatory Markers on the Association of Dietary Insulin Index and Insulin Load with Metabolic Syndrome in Women with Overweight and Obesity: A Cross-Sectional Study

Table 3

Association between MetS and its components with DIL and DII in obese and overweight women (n = 219).


Variables		DII median			DIL median
Variables		OR	95% CI	value	OR	95% CI	value

WC (cm)	Crude	1.21	0.58, 2.53	0.60	0.94	0.45, 1.96	0.88
	Model 1	1.46	0.63, 3.41	0.37	1.07	0.31, 3.65	0.90
	Model 2	1.67	1.09, 4.03	0.03	1.27	0.34, 4.72	0.71

TG (mg/dL)	Crude	0.83	0.44, 1.56	0.56	0.83	0.44, 1.56	0.56
	Model 1	1.26	0.61, 2.61	0.51	1.28	0.42, 3.86	0.65
	Model 2	1.10	0.92, 2.33	0.07	1.20	0.38, 3.84	0.74

HDL-C (mg/dL)	Crude	1.10	0.62, 1.93	0.73	1.07	0.61, 1.88	0.81
	Model 1	0.98	0.52, 1.84	0.95	0.77	0.29, 2.04	0.59
	Model 2	1.15	0.59, 2.23	0.67	0.81	0.28, 2.33	0.70

FBG (mg/dL)	Crude	1.14	0.39, 3.27	0.80	1.16	0.40, 3.33	0.77
	Model 1	0.56	0.16, 1.92	0.36	0.58	0.09, 3.71	0.56
	Model 2	0.65	0.18, 2.39	0.52	0.66	0.08 5.01	0.69

SBP (mm Hg)	Crude	1.53	0.52, 4.53	0.43	1.41	0.54, 3.68	0.47
	Model 1	1.14	0.38, 3.39	0.81	0.50	0.09, 2.78	0.43
	Model 2	1.25	0.38, 4.07	0.70	0.52	0.08, 3.46	0.50

DBP (mm Hg)	Crude	1.88	0.95, 3.71	0.06	1.79	0.90, 3.53	0.09
	Model 1	1.59	0.75, 3.37	0.22	2.09	0.67, 6.50	0.19
	Model 2	1.54	0.70, 3.42	0.28	2.05	0.61, 6.87	0.24

SBP/DBP (mmHg)	Crude	2.12	1.10, 4.11	0.02	1.62	0.84, 3.10	0.14
	Model 1	1.71	0.82, 3.55	0.14	1.58	0.53, 4.74	0.40
	Model 2	1.84	0.85, 3.99	0.07	1.74	1.54, 5.61	0.04

MetS	Crude	1.56	0.78, 3.12	0.20	1.13	0.57, 1.21	0.71
	Model 1	1.63	0.76, 3.51	0.20	1.06	0.35, 2.65	0.90
	Model 2	2.11	0.93, 4.82	0.06	1.59	0.21, 2.21	0.45

CI: confidence interval, DBP: diastolic blood pressure, DIL: dietary insulin load, DII: dietary insulin index, FBG: fasting blood glucose, HDL_C: high-density lipoprotein cholesterol, MetS: metabolic syndrome, OR: odds ratio, SBP: systolic blood pressure, TG: triglyceride, and WC: waist circumference. Binary logistic regression was used. The lower median of DIL (<97155.69) and DII (>38.82) is considered a reference group. Model 1: adjusted for age, BMI, energy intake, and physical activity (BMI consider a collinear variable). Model 2: model 1+ education, marital, and economic status. values <0.05 were considered significant. P values 0.05–0.07 are considered marginally significant. values marked in bold show significant or marginally significant association.