The Possible Mediatory Role of Inflammatory Markers on the Association of Dietary Insulin Index and Insulin Load with Metabolic Syndrome in Women with Overweight and Obesity: A Cross-Sectional Study

Table 4

MetS and its components among DIL and DII in obese and overweight women (n = 219).

Variables		DII median			DIL median
		OR	95% CI	value	OR	95% CI	value
WC (cm)	hs_CRP	1.65	0.65, 4.14	0.28	1.19	0.30, 4.71	0.80
	MCP-1	1.44	0.57, 3.65	0.43	1.47	0.23, 9.24	0.67
TG (mg/dL)	hs_CRP	1.23	0.55, 2.71	0.60	1.27	0.37, 4.39	0.69
	MCP-1	1.34	0.57, 3.10	0.49	1.57	0.44, 5.61	0.48
HDL-c (mg/dL)	hs_CRP	1.12	0.57, 2.22	0.73	0.67	0.23, 1.99	0.47
	MCP-1	0.99	0.49, 2.00	0.98	0.93	0.30, 2.82	0.90
FBG (mg/dL)	hs_CRP	0.50	0.10, 2.33	0.37	0.43	0.03, 5.53	0.52
	MCP-1	0.73	0.18, 2.95	0.66	0.37	0.04, 3.28	0.37
SBP (mmHg)	hs_CRP	1.20	0.35, 4.04	0.76	0.44	0.06, 3.14	0.41
	MCP-1	1.59	0.34, 7.36	0.54	0.45	0.04, 4.84	0.51
DBP (mmHg)	hs_CRP	1.56	0.65, 3.69	0.31	1.83	0.49, 6.81	0.36
	MCP-1	1.95	0.76, 4.98	0.16	2.96	0.73, 11.99	0.12
SBP/DBP (mmHg)	hs_CRP	1.88	0.82, 4.33	0.13	1.49	0.42, 5.28	0.53
	MCP-1	2.43	0.98, 5.99	0.05	2.33	0.622, 8.75	0.20
MetS	hs_CRP	0.38	0.15, 0.96	0.03	0.63	0.16, 2.40	0.50
	MCP-1	2.08	0.83, 5.20	0.11	1.53	0.39, 5.87	0.53

CI: confidence interval, DBP: diastolic blood pressure, DIL: dietary insulin load, DII: dietary insulin index, FBG: fasting blood glucose, HDL_C: high-density lipoprotein cholesterol, hs-CRP: high-sensitivity c-reactive protein, MetS: metabolic syndrome, MCP-1: monocyte chemoattractant protein-1, OR: odds ratio, SBP: systolic blood pressure, TG: triglyceride, and WC: waist circumference. Binary logistic regression was used. The lower median of DIL (<97155.69) and DII (<38.82) consider a reference group. hs_CRP: adjusted for age, energy intake, physical activity, education status, marital status, economic status, and hs_CRP. MCP-1: adjusted for age, energy intake, physical activity, education status, marital status, economic status, and MCP-1.