Research Article

The Association between Deoxyribonucleic Acid Hypermethylation in Intron VII and Human Leukocyte Antigen-C07 Expression in Patients with Endometriosis

Table 1

General characteristics and HLA-C typing of the study participants.

Microarray studyPatients with ovarian endometriosis (n = 6)Healthy controls (n = 6)

Age (years, mean ± SD)33.4 ± 4.132.5 ± 3.6
BMI (kg/m2, mean ± SD)24.2 ± 3.225.1 ± 2.9
Stage I-II (n)4NA
Stage III-IV (n)2NA
HLA-C typing
HLA-C07 carrier (n)63
Non-HLA-C07 carrier (n)03

Validation studyPatients with ovarian endometriosis (n = 22)Healthy controls (n = 26)
Age (years, mean ± SD)32.3 ± 3.832.9 ± 4.3
BMI (kg/m2, mean ± SD)22.2 ± 3.924.3 ± 3.4
Stage I-II (n)16NA
Stage III-IV (n)6NA
HLA-C typing
HLA-C07 carrier (n)88
Non-HLA-C07 carrier (n)1418

NA, not applicable.