Research Article

Postoperative Adjuvant Treatment in Women with Stage I Endometrial Cancer: A Retrospective Study

Table 1

Patient and tumor characteristics.

CharacteristicA groupB groupC groupD group-value
N88116627

Age (%)0.2823
 <60 y69 (78.41)7 (63.64)55 (83.33)24 (88.89)
 ≥60 y19 (21.59)4 (36.36)11 (16.67)3 (11.11)
Histologic type (%)0.7971
 Adenocarcinoma81 (92.04)11 (100)62 (93.93)27 (100)
 Adenocarcinoma (mesonephric-like)3 (3.41)0 (0)0 (0)0 (0)
 Clear cell carcinoma1 (1.14)0 (0)3 (4.55)0 (0)
 Mucinous papillary (adenocarcinoma of intestinal epithelium)1 (1.14)0 (0)0 (0)0 (0)
 Papillary adenocarcinoma (villous-tubular carcinoma subtype)0 (0)0 (0)1 (1.52)0 (0)
 Serous papillary carcinoma2 (2.27)0 (0)0 (0)0 (0)
Histologic grade (%)
 G164 (72.73)4 (36.36)26 (39.40)20 (74.07)
 G217 (1932)5 (4545)30 (4545)5 (1852)
 G33 (3.41)2 (18.18)8 (12.12)2 (7.41)
 Unknown4 (4.54)0 (0)2 (3.03)0 (0)
FIGO stage (%)
 IA80 (90.91)7 (63.64)49 (74.24)23 (85.19)
 IB8 (9.09)4 (36.36)17 (25.76)4 (14.81)
Lymphadenectomy
 Pelvic lymph node62 (70.45)9 (81.82)54 (81.82)21 (77.78)0.9688
 Pelviclymph + para-aortic node12 (12.5)1 (0.91)8 (12.12)1 (3.7)0.4211
CA1250.395
 <35 U/ml40 (45.45)6 (54.55)35 (53.03)10 (37.04)
 ≥35 U/ml11 (12.50)2 (18.18)6 (9.09)1 (3.70)
 Unknown37 (42.05)3 (27.27)25 (37.88)16 (59.26)
ER (%)0.0743
 +48 (54.55)10 (90.91)49 (74.24)17 (62.97)
 −8 (9.09)0 (0)6 (9.09)1 (3.70)
 Unknown32 (36.36)1 (9.09)11 (16.67)9 (33.33)
PR (%)
 +41 (46.59)7 (63.64)45 (68.18)18 (66.67)
 −15 (17.05)3 (27.27)9 (13.64)0 (0)
 ±0 (0)0 (0)1 (1.52)0 (0)
 Unknown32 (36.36)1 (9.09)11 (16.66)9 (33.33)

A group, no adjuvant treatment; B group: radiotherapy; C group, chemotherapy; D group, MPA + chemotherapy (or) radiotherapy. Abbreviations: FIGO, international federation of gynecology and obstetrics; CA125, carbohydrate antigen-125; ER, estrogen receptor; PR, progesterone receptor. .