Leptin Receptor Gln223Arg Polymorphism of Human Spermatozoa Associated with Male Infertility in a Chinese Population

Table 4

Semen variables of primary infertility, secondary infertility, and controls partitioned by genotypes of LEPR Gln223Arg polymorphisms.

Semen variables	Primary infertility	Secondary infertility		Controls			value
	AA + AG (n = 27)	GG (n = 81)	AA + AG (n = 30)	GG (n = 68)	AA + AG (n = 36)	GG (n = 79)
Semen volume (ml)	3.99 (2.6–5.1)	3.27 (1.8–4.55)	3.52 (2.4–4.3)	3.25 (2.1–4.25)	3.10 (2.2–4.05)	3.35 (2.2–4.2)	0.1977
Sperm counts (million/ml)	40.91 (12–42.7)	29.54 (2–41.05)	58.07 (26.3–80.9)	53.94 (17.25–65.65)	62.31 (39.3–80.2)	69.38 (33.5–90.6)	0.5753
Sperm motility (%)	31.98 (23.2–39.1)	34.54 (19.8–52.1)	32.96 (27.2–38.7)	34.41 (23.65–45.35)	56.12 (43.65 - 66.15)	59.36 (50–68)
Sperm normal morphology (%)	2.93 (1–4)	3.12 (1–5)	4.97 (3–7)	3.71 (2–6)	5.94 (4–7)	6.54 (5–8)

value <0.05. Significant difference between AA + AG and GG among primary infertility, secondary infertility, and controls. Results are presented as median (interquartile range).