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Case | Age (y) | Obstetric anamnesis | Time of GTD detection (GW) | P type | P outcome | Ultrasound data | MRI data | Histological form | β-hCG titer (3 weeks postnatal follow-up) | Presence of metastatic lesions (localization) | Treatment |
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N1 | 31 | P-0 | 11 | Singleton pregnancy | Termination of pregnancy for obstetrical/medical reasons | Hyperechogenic reticular, cellular structure. Retrochorial hematoma. | Multicystic pathological formation, numerous vessels. The contact area is uneven, indistinct. Retroplacental vascularization/neovascularization. Adhesion areas (5.0–5.5 cm). Subchorionic hematoma. Mild collateralization. | Invasive mole | Plateau | Pulmonary | Chemotherapy Mtx/FA, dactinomycin |
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N2 | 36 | P-4, A-1, D-3, Ln-3 | 10 | Diamniotic dichorionic twins | Childbirth 27 GW | Hyperechogenic formation of heterogeneous structure with anechogenic multifaceted inclusions. Retrochorial hematoma. | The lower amniotic cavity and placenta are replaced by pathological tissue of heterogeneous cystic structure. Contours indistinct, rough, infiltration of the anterior uterine wall. Collateralization in the inferior segment. Retroplacental vascularization/neovascularization. Subamniotic hematoma. | Choriocarcinoma in one placenta | Plateau | Pulmonary | Chemotherapy Mtx/FA |
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N3 | 32 | P-2, A-1, D-1, Ln-1 | 16 | Singleton pregnancy | Childbirth 28 GW | One-third of the placenta with cystic inclusions. Subamniotic hematoma. | Cellular structures of irregular shape. The surface of the placenta is rough, with a lumpy contour. Retroplacental and intramural vascularization. | Intraplacental choriocarcinoma | Plateau | Pulmonary | Chemotherapy Mtx/FA |
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N4 | 36 | P-0 | 19 | Diamniotic dichorionic twins | Childbirth 33 GW | The formation of a cellular structure. | Placental overgrowth in the form of cysts of various diameters. | Noninvasive mole of a single fetus | Normalisation | Absent | None, observation |
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N5 | 31 | P-1, D-1, Fd-1 | 11 | Diamniotic dichorionic twins | Termination of pregnancy for medical reasons | Formation of a cellular structure. Theca lutein cysts. Subamniotic hematoma. | Multicystic masses surround the amniotic cavity, subtotally filling the uterine cavity. Majority parts of both placentas are represented by pathological multicystic structures. Subamniotic hematoma. The boundaries with myometrium are clear, smooth. Theca lutein cysts. | Noninvasive mole of both fetuses | Normalisation | Absent | None, observation |
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