Identification of Crotonylation Metabolism Signature Predicting Overall Survival for Clear Cell Renal Cell Carcinoma

Figure 3

Construction and validation of the crotonylation metabolism-related signature. (a) Differences in crotonylation metabolism-related genes expression between ccRCC and normal tissues. (b) Results of univariate Cox regression analysis. (c) LASSO regression identified 4 crotonylation metabolism-related genes. (d) Distribution of modeled genes and clinicopathologic features between crotonylation metabolism signatures. (e) The risk curve of each sample reordered by crotonylation metabolism-related signature and the distribution of survival states. (f) Survival analysis of the crotonylation metabolism signature. (g) ROC curves about crotonylation metabolism-related signature in 1–3 years. (h, i) The results of univariate and multivariate Cox analysis of crotonylation metabolism-related signature. (j) Risk curve of each sample reordered by crotonylation metabolism signature and the distribution of survival states in GSE22541. (k) Survival analysis of the crotonylation metabolism signature in GSE22541. (l) ROC curves about crotonylation metabolism signature in 1–3 years in GSE22541.

(a)

(b)

(c)

(d)

(e)

(f)

(g)

(h)

(i)

(j)

(k)

(l)