Identification of Crotonylation Metabolism Signature Predicting Overall Survival for Clear Cell Renal Cell Carcinoma

Figure 8

Downregulation of KAT2A suppressed the progression of ccRCC in vitro. (a) mRNA differential expression of KAT2A in ccRCC tissues and cell lines. (b) The expression of KAT2A in A498 and 786-O cells was detected by RT-qPCR. (c) KAT2A knockdown suppressed ccRCC cell proliferation in A498 and 786-O cells. (d) KAT2A knockdown suppressed ccRCC cell metastasis in A498 and 786-O cells. (e) Wound healing tests demonstrated changes in ccRCC cell migration.

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