Relationship between Body Mass Index and Bone Turnover Markers in Girls with Idiopathic Central Precocious Puberty

Table 2

Levels of bone turnover markers in different groups.

BTMs	Normal weight (n = 89)	Overweight (n = 70)	Obese (n = 52)	value
P1NP (ng/ml)	994.60 (867.30–1123.50)^a	950.40 (791.25–1081.00)^b	712.20 (619.40–1063.00)^c	<0.001
N-MID (pg/ml)	76.47 (62.98–90.19)	71.79 (60.42–93.61)	74.18 (62.20–84.20)	0.486
β-CTX (ng/ml)	1560.00 (1170.00–1806.00)	1540.00 (1234.00–1760.00)	1425.00 (957.20–1850.00)	0.713

^aSignificantly different from the overweight group. ^bSignificantly different from the obese group. ^cSignificantly different from the normal weight group. BTMs, bone turnover markers; P1NP, total procollagen type 1 N-terminal propeptide; N-MID, N-terminal midfragment of osteocalcin; β-CTX, β-C-terminal telopeptide of type 1 collagen.