Mean Nocturnal Baseline Impedance (MNBI) Provides Evidence for Standardized Management Algorithms of Nonacid Gastroesophageal Reflux-Induced Chronic Cough
Table 1
Demographic and clinical characteristics of responders and nonresponders.
Responders (n = 50)
Nonresponders (n = 40)
value
Gender (male/female)
27/23
20/20
0.775
Age (years)
50.14 ± 12.29
41.27 ± 14.33
0.323
Duration of cough (months)
48.00 (18.00, 89.50)
36.00 (12.00, 84.00)
0.731
GerdQ score
6.00 (6.00, 6.50)
6.00 (6.00, 7.50)
0.801
Cough symptom score
Daytime
3.50 (3.00, 4.00)
3.00 (3.00, 4.00)
0.596
Nighttime
1.00 (1.00, 2.50)
1.00 (1.00, 2.00)
0.885
Capsaicin cough threshold
C2 (μmol/L)
0.91 ± 0.22
1.19 ± 0.14
0.622
C5 (μmol/L)
2.63 ± 0.23
2.14 ± 0.15
0.754
Lung function
FEV1% pred
105.44 ± 9.75
95.17 ± 13.44
0.247
FVC% pred
113.70 ± 11.09
95.42 ± 14.24
0.399
FEV1/FVC (%)
79.99 ± 6.47
84.36 ± 6.63
0.979
Data are presented as the mean ± SD, median (interquartile range), or no. (%) unless otherwise indicated; C2, capsaicin solution concentration for ≥2 coughs; C5, capsaicin solution concentration for ≥ 5 coughs; GerdQ, gastroesophageal reflux diagnostic questionnaire; FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity.
