Mean Nocturnal Baseline Impedance (MNBI) Provides Evidence for Standardized Management Algorithms of Nonacid Gastroesophageal Reflux-Induced Chronic Cough

Table 4

Comparison of proximal MNBI and weakly acid reflux value in predicting the efficacy of standard antireflux therapy.

Standard	Sensitivity (%)	Specificity (%)	Positive predictive value (%)	Negative predictive value (%)	AUCROC	Youden index	Kappa value
A	92.86	70.00	68.42	93.33	0.814	0.629	0.597
B	62.96	74.29	65.20	72.22	0.686	0.373	0.374
A and B	50.00	96.55	90.0	75.68	0.733	0.466	0.508
A or B	84.21	52.38	61.54	78.57	0.683	0.366	0.360
χ ^2	4.885	4.394	11.394	2.814
	0.001	0.006	0.034	0.032

A, proximal MNBI < 2140 Ω; B, weakly acid reflux > 45; MNBI, mean nocturnal baseline impedance; OR, odds ratio.